The Domain Name System of the Internet consists of a set of top-level domains which constitute the root domain of the hierarchical name space and database. In the growth of the Internet, it became desirable to expand the set of initially six generic top-level domains in 1984. As a result new top-level domain names have been proposed for implementation by ICANN. Such proposals included a variety of models ranging from adoption of policies for unrestricted gTLDs that could be registered by anyone for any purpose, to chartered gTLDs for specialized uses by specialized organizations. In October 2000, ICANN published a list of proposals for top-level domain strings it had received.
.ln and .le - Currently being sold by Dennis Hope's "Lunar Embassy Commission" alongside .lunar, .moon, .venus, .mars, .jupiter, .saturn, .uranus, .neptune, .pluto, .space. People who purchase novelty deeds for outer space property from him are also given free domains. None of these TLDs are supported at present by root servers.
Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28gene. It forms part of the Mediator complex.
Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the head module, and components of this submodule act together in a gene-regulatory programme to suppress smooth musclecell differentiation. Thus, mammalian Mediator subunit Med28 functions as a repressor of smooth muscle-cell differentiation, which could have implications for disorders associated with abnormalities in smooth musclecell growth and differentiation, including atherosclerosis, asthma, hypertension, and smooth muscle tumours.
Tyrosine-protein kinase Tec is an enzyme that in humans is encoded by the TECgene.
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein-coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
The TEC-1 is a single-board kit computer first produced by the Australian hobbyist electronics magazine Talking Electronics in the early 1980s. It was based on the Zilog Z80 CPU, had 2K of RAM and 2K of ROM in a default configuration. Later versions used a 4k ROM with two different versions of the monitor software selectable via a switch. This allowed the early software presented in the magazine to be used with the later version of the TEC-1.
The base configuration had 20 keys for the main input (16 hexadecimal keys for numeric input and keys labelled AD (for address), GO (to execute a program), + and -. There was also a reset key in the standard configuration and an optional upgrade had a function key.
It was featured in 1983, in Volume 1, Issue 10 of the Talking Electronics magazine, pages 57 to 75, with relevant chip data presented on the rear cover.
The series continued in early 1984 with Volume 1, Issue 11, pages 11 to 36, and pages 50 to 55. Included in this page count were two peripherals for the TEC-1 -an 8x8 matrix display, and a relay driver board, allowing the TEC-1 to be interfaced to other equipment.
Nano returned to the second level in the 2009–10 campaign, being relatively played by Cádiz CF but suffering team relegation. He scored his first goal as a professional on 4 October 2009, in a 1–0 away win against Albacete Balompié.